Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203812 | 0.84 | CYP19A1 (0.62) | CYP19A1TSHRALDH1A1HIF1AHSPB1 | |
| SCHEMBL1172437 | 0.84 | CYP19A1 (0.55) | CYP19A1TSHRALDH1A1HIF1AHSPB1 | |
| SCHEMBL27966500 | 0.84 | CYP19A1 (0.62) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| Fluoride SCHEMBL27574861 | 0.81 | CYP19A1 (0.59) | CYP19A1TSHRALDH1A1HIF1AHSPB1 | |
| SCHEMBL16960250 | 0.74 | CYP19A1 (0.44) | CYP19A1TSHRALDH1A1HIF1AHSPB1 | |
| SCHEMBL2649497 | 0.74 | CYP19A1 (0.44) | CYP19A1TSHRALDH1A1HIF1AHSPB1 | |
| SCHEMBL1944691 | 0.74 | ALDH1A1 (0.50) | CYP19A1TSHRALDH1A1MEN1HTT | |
| SCHEMBL8999906 | 0.74 | ALDH1A1 (0.50) | CYP19A1TSHRALDH1A1HIF1AHSPB1 | |
| SCHEMBL29277770 | 0.74 | TSHR (0.71) | CYP19A1TSHRALDH1A1LMNAMEN1 | |
| SCHEMBL30492205 | 0.74 | LMNA (0.47) | CYP19A1TSHRALDH1A1HIF1AHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448534-A1 | 6-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OFTHE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003029224-A1 | 6-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |