SCHEMBL6648069

SCHEMBL6648069

CC1c2cc(Br)sc2CN1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29970524 0.84 SMN1; SMN2 (0.37) PNMTSMN1; SMN2
SCHEMBL28455409 0.77 PNMT (0.41) PNMT
SCHEMBL18640508 0.70 CAMK2A (0.42) PNMT
SCHEMBL21236297 0.69 UCHL1 (0.36) SMN1; SMN2
SCHEMBL28449413 0.68 SMN1; SMN2 (0.36) PNMTSMN1; SMN2
SCHEMBL29971027 0.68 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL2838035 0.63 NPC1 (0.36) PNMT
SCHEMBL16056609 0.63
SCHEMBL20741820 0.61 HDAC6 (0.47) SMN1; SMN2
SCHEMBL984158 0.61 HDAC6 (0.47) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401830-A2 QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS Warner-Lambert Company LLC (US) 2004-03-31 EP disclosed
WO-2002102793-A2 QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY LLC (US) 2002-12-27 WO disclosed