Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | BAD | Q92934 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449170 | 0.81 | — | — | |
| SCHEMBL6648069 | 0.77 | PNMT (0.34) | PNMT | |
| SCHEMBL31335948 | 0.72 | HSD17B3 (0.45) | PNMT | |
| SCHEMBL29970524 | 0.69 | SMN1; SMN2 (0.37) | PNMTKCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL15355395 | 0.68 | OPRM1 (0.49) | BCL2BADALDH1A1 | |
| SCHEMBL984158 | 0.68 | HDAC6 (0.47) | KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL28449413 | 0.68 | SMN1; SMN2 (0.36) | PNMTALDH1A1 | |
| SCHEMBL23327054 | 0.67 | OPRK1 (0.46) | — | |
| SCHEMBL25429344 | 0.66 | ABHD6 (0.41) | ALDH1A1 | |
| SCHEMBL25431503 | 0.66 | ABHD6 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922430-B | 2-substituted benzimidazole-4-formamide compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-09-04 | — | — | CN | disclosed |