Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675930 | 0.94 | TRPM5 (0.50) | TRPM5KMT2AKDM4ENR4A2MAPK1 | |
| SCHEMBL6654159 | 0.85 | TRPM5 (0.40) | TRPM5HRH1KMT2AKDM4EMAPK1 | |
| SCHEMBL6648694 | 0.82 | TRPM5 (0.38) | TRPM5HRH1KMT2AKDM4EMAPK1 | |
| SCHEMBL6651875 | 0.81 | SMN1; SMN2 (0.48) | TRPM5HRH1KDM4ENPC1RAB9A | |
| SCHEMBL6650448 | 0.80 | TRPM5 (0.41) | TRPM5KMT2AKDM4ENR4A2MAPK1 | |
| SCHEMBL6653862 | 0.79 | CYP1A2 (0.35) | TRPM5HRH1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6654254 | 0.78 | TRPM5 (0.37) | TRPM5KMT2AKDM4ENR4A2HPGD | |
| SCHEMBL6650011 | 0.76 | DRD4 (0.40) | HRH1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6650126 | 0.75 | DRD4 (0.34) | TRPM5HRH1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6654434 | 0.74 | DRD4 (0.37) | TRPM5HRH1KMT2AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |