Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654159 | 0.93 | TRPM5 (0.40) | TRPM5KMT2AKDM4EMEN1LMNA | |
| SCHEMBL6651869 | 0.86 | GPR6 (0.35) | TRPM5KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6650633 | 0.85 | ALDH1A1 (0.38) | TRPM5KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6675930 | 0.83 | TRPM5 (0.50) | TRPM5KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6650585 | 0.82 | HRH3 (0.37) | — | |
| SCHEMBL6672324 | 0.81 | KDM4E (0.33) | TRPM5KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6649239 | 0.80 | TRPM5 (0.49) | TRPM5KMT2AKDM4EALDH1A1MAPK1 | |
| SCHEMBL6648867 | 0.80 | SLC6A4 (0.32) | KMT2AKDM4EALDH1A1MEN1LMNA | |
| SCHEMBL6649431 | 0.78 | DRD4 (0.37) | TRPM5KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL6648442 | 0.76 | HRH3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |