Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649239 | 0.81 | TRPM5 (0.49) | KDM4ENPC1RAB9AHRH1TRPM5 | |
| SCHEMBL6675930 | 0.79 | TRPM5 (0.50) | SMN1; SMN2KDM4ELMNATRPM5DRD2 | |
| SCHEMBL14970726 | 0.74 | TSHR (0.54) | SMN1; SMN2KDM4ENPC1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL14966454 | 0.73 | TSHR (0.52) | SMN1; SMN2KDM4ENPC1RAB9ALMNA | |
| SCHEMBL12120425 | 0.73 | CYP1A2 (0.54) | SMN1; SMN2KDM4ENPC1RAB9ALMNA | |
| SCHEMBL1307575 | 0.71 | TSHR (0.53) | SMN1; SMN2KDM4ENPC1RAB9ALMNA | |
| SCHEMBL6651515 | 0.70 | KMT2A (0.48) | SMN1; SMN2NPC1RAB9ALMNATRPM5 | |
| SCHEMBL3536478 | 0.70 | HRH3 (0.53) | HRH1HRH3 | |
| SCHEMBL14970666 | 0.70 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4ENPC1RAB9ALMNA | |
| SCHEMBL6650687 | 0.69 | KMT2A (0.47) | SMN1; SMN2NPC1RAB9ALMNATRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |