Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823668 | 1.00 | LMNA (0.59) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL293067 | 0.90 | IDO1 (0.57) | LMNAAKR1B10AKR1B1MMP1MMP2 | |
| SCHEMBL4651145 | 0.82 | LMNA (0.61) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL3292040 | 0.82 | MEN1 (0.51) | LMNAMMP1MMP2MMP9MMP12 | |
| SCHEMBL3292037 | 0.82 | MEN1 (0.51) | LMNAMMP1MMP2MMP9MMP12 | |
| SCHEMBL28425115 | 0.81 | MMP1 (0.52) | LMNAMMP1MMP2MMP9MMP12 | |
| SCHEMBL37382 | 0.80 | ALDH1A1 (0.68) | LMNACA12CA9ALDH1A1HCAR2 | |
| SCHEMBL1158019 | 0.80 | MMP1 (0.51) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL1158016 | 0.80 | MMP1 (0.51) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL13923795 | 0.80 | MMP1 (0.51) | LMNAAKR1B10AKR1B1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154980-B1 | METHOD FOR PRODUCING SYMMETRICAL AND ASYMMETRICAL CARBONATES | GOEDECKE GMBH (DE) | 2004-05-26 | — | — | EP | disclosed |
| US-6740768-B1 | REACTING ALKYL OR ARYL ALCOHOL AND HALIDE WITH CARBON DIOXIDE AND CESIUM CARBONATE AT ROOM TEMPERATURE IN DIPOLAR APROTIC SOLVENT | GOEDECKE GMBH (DE) | 2004-05-25 | — | — | US | disclosed |
| EP-1154980-A1 | METHOD FOR PRODUCING SYMMETRICAL AND ASYMMETRICAL CARBONATES | GÖDECKE GMBH (DE) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047544-A1 | METHOD FOR PRODUCING SYMMETRICAL AND ASYMMETRICAL CARBONATES | Gödecke GmbH (DE) | 2000-08-17 | — | — | WO | disclosed |