Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651323 | 1.00 | TP53 (0.54) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL19941727 | 0.86 | TP53 (0.62) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL6862095 | 0.86 | TP53 (0.62) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL19942011 | 0.86 | TP53 (0.62) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL4491334 | 0.84 | THRB (0.61) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL4970293 | 0.81 | TP53 (0.57) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL9488672 | 0.81 | TP53 (0.57) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL20930470 | 0.80 | TP53 (0.44) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL17073955 | 0.80 | TP53 (0.49) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL27908674 | 0.80 | THRB (0.61) | TP53ALDH1A1NPSR1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489504-B2 | Malic acid and oxalacetic acid derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-12-03 | — | — | US | claimed |
| EP-3473098-A1 | COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF | Gorbunov, Sergei Valeryevich (RU) | 2019-04-24 | — | — | EP | disclosed |
| EP-1132369-B1 | Malic acid and oxalacetic acid derivatives | DAICEL CHEM (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-6489504-B2 | Malic acid and oxalacetic acid derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-12-03 | — | — | US | disclosed |
| US-20010056120-A1 | Malic acid and oxalacetic acid derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-27 | — | — | US | disclosed |
| EP-1132369-A1 | Malic acid and oxalacetic acid derivatives | Daicel Chemical Industries, Ltd. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056120-A1 | Malic acid and oxalacetic acid derivatives | ME1, ME3, MLYCD | TP53 2541/4885ALDH1A1 107/4885NPSR1 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.