Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521527 | 0.72 | RAB9A (0.48) | TBXAS1LMNAHDAC3TNKSHDAC4 | |
| SCHEMBL7521545 | 0.72 | RAB9A (0.48) | TBXAS1LMNAHDAC3TNKSHDAC4 | |
| SCHEMBL6805605 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1LMNAGABRA1 | |
| SCHEMBL6804116 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPK1LMNAGABRA1 | |
| Hydrochloric Acid SCHEMBL6805332 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPK1LMNAGABRA1 | |
| SCHEMBL6650197 | 0.70 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPK1LMNAGABRA1 | |
| SCHEMBL13160968 | 0.70 | MAPK1 (0.48) | ALDH1A1TDP1MAPK1LMNAGABRA1 | |
| SCHEMBL8370307 | 0.69 | TBXAS1 (0.41) | ALDH1A1TBXAS1LMNAHDAC3TNKS | |
| SCHEMBL10414515 | 0.69 | TBXAS1 (0.41) | ALDH1A1TBXAS1LMNAHDAC3TNKS | |
| SCHEMBL7605105 | 0.69 | CYP11B1 (0.49) | TBXAS1LMNACYP3A4CYP1A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970073-B1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-0973769-B1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2004-08-25 | — | — | EP | disclosed |