Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3568945 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL6805605 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL6804116 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL6805332 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL7521534 | 0.71 | RAB9A (0.49) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL24967052 | 0.71 | ALDH1A1 (0.78) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL6650195 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL7340516 | 0.69 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL6806534 | 0.69 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11496011 | 0.68 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970073-B1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-0973769-B1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2004-08-25 | — | — | EP | disclosed |