Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646708 | 0.83 | KMT2A (0.43) | MMP13MMP1 | |
| SCHEMBL3510826 | 0.76 | SOD1 (0.44) | SOD1THRB | |
| SCHEMBL878654 | 0.73 | SOD1 (0.48) | SOD1S1PR1 | |
| SCHEMBL10409513 | 0.70 | SOD1 (0.46) | SOD1THRBPGRS1PR1 | |
| SCHEMBL10409528 | 0.68 | TRPV4 (0.40) | SOD1NR3C1PGR | |
| SCHEMBL8745524 | 0.67 | SOD1 (0.50) | SOD1PGRS1PR1 | |
| SCHEMBL28159313 | 0.67 | SOD1 (0.40) | SOD1THRBS1PR1 | |
| SCHEMBL23159246 | 0.66 | SOD1 (0.35) | SOD1NR3C1PGRNR3C2S1PR1 | |
| SCHEMBL4011416 | 0.66 | CA2 (0.52) | SOD1THRB | |
| SCHEMBL6651429 | 0.66 | SOD1 (0.34) | SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451191-A1 | THIOETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003050121-A1 | THIOETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |