Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650231 | 0.83 | SOD1 (0.37) | MMP1MMP13 | |
| SCHEMBL1368829 | 0.76 | KMT2A (0.51) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL198600 | 0.73 | PSIP1 (0.58) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL11658315 | 0.72 | ALDH1A1 (0.50) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL15899648 | 0.72 | MMP2 (0.50) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL10389514 | 0.72 | ALDH1A1 (0.52) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL10567409 | 0.71 | NPC1 (0.46) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL26377170 | 0.70 | THRB (0.52) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL426162 | 0.70 | ALDH1A1 (0.52) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL10724186 | 0.69 | ALDH1A1 (0.48) | KMT2AGAAMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451191-A1 | THIOETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003050121-A1 | THIOETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |