Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650405 | 0.85 | KMT2A (0.38) | CASP6KMT2AMEN1OPRK1NAMPT | |
| SCHEMBL6651515 | 0.83 | KMT2A (0.48) | KMT2AMEN1OPRK1FDPSMAPT | |
| SCHEMBL6650608 | 0.79 | OPRK1 (0.43) | KMT2AMEN1OPRK1FDPSKDM4E | |
| SCHEMBL4063363 | 0.73 | FDPS (0.48) | KMT2AMEN1OPRK1FDPSKDM4E | |
| SCHEMBL6651869 | 0.73 | GPR6 (0.35) | KMT2AMEN1KDM4EGAAMAPT | |
| Formic Acid SCHEMBL30454816 | 0.73 | KMT2A (0.44) | KMT2AMEN1OPRK1FDPSKDM4E | |
| SCHEMBL6649403 | 0.71 | KMT2A (0.39) | KMT2AMEN1OPRK1FDPSALDH1A1 | |
| SCHEMBL6650687 | 0.70 | KMT2A (0.47) | KMT2AMEN1OPRK1FDPSMAPT | |
| SCHEMBL15236207 | 0.69 | — | — | |
| SCHEMBL6653570 | 0.68 | HSP90AA1 (0.46) | KMT2AMEN1OPRK1FDPSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |