Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650448 | 0.86 | TRPM5 (0.41) | KDM4EGAAMAPTKMT2AMEN1 | |
| SCHEMBL6654159 | 0.80 | TRPM5 (0.40) | KDM4EMAPTKMT2AMEN1LMNA | |
| SCHEMBL6672324 | 0.76 | KDM4E (0.33) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6650405 | 0.76 | KMT2A (0.38) | KDM4EGAAMAPTKMT2AMEN1 | |
| SCHEMBL6649431 | 0.74 | DRD4 (0.37) | KMT2AMEN1LMNATRPM5SMN1; SMN2 | |
| SCHEMBL6650433 | 0.73 | CASP6 (0.43) | KDM4EGAAMAPTKMT2AMEN1 | |
| SCHEMBL6675930 | 0.71 | TRPM5 (0.50) | KDM4EGAAMAPTKMT2AMEN1 | |
| SCHEMBL6654434 | 0.71 | DRD4 (0.37) | KDM4EKMT2AMEN1LMNATRPM5 | |
| SCHEMBL6650126 | 0.70 | DRD4 (0.34) | KMT2AMEN1LMNATRPM5 | |
| SCHEMBL6650585 | 0.69 | HRH3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |