Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | FEN1 | P39748 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614630 | 0.84 | CCNC (0.35) | APOL1LIPG | |
| SCHEMBL6614624 | 0.84 | CCNC (0.35) | APOL1LIPG | |
| SCHEMBL6613404 | 0.80 | CRBN (0.37) | APOL1DDB1CRBN | |
| SCHEMBL6613347 | 0.80 | APOL1 (0.37) | APOL1DDB1CRBN | |
| SCHEMBL6613354 | 0.80 | APOL1 (0.37) | APOL1DDB1CRBN | |
| SCHEMBL6613398 | 0.80 | CRBN (0.37) | APOL1DDB1CRBN | |
| SCHEMBL6645760 | 0.78 | FPR2 (0.36) | APOL1FPR2DDB1CRBN | |
| SCHEMBL6645767 | 0.78 | FPR2 (0.36) | APOL1FPR2DDB1CRBN | |
| SCHEMBL6672074 | 0.73 | KDM4E (0.41) | — | |
| SCHEMBL6672070 | 0.73 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456172-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053925-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-07-03 | — | — | WO | disclosed |