Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.46 |
| ▸ | TUBB | P07437 | 5/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872783 | 0.86 | MAPT (0.58) | GAAKMT2AHSD17B10STSLMNA | |
| SCHEMBL29986971 | 0.85 | MAPT (0.57) | GAAKMT2AHSD17B10STSLMNA | |
| SCHEMBL322169 | 0.85 | MAPT (0.57) | GAAKMT2AHSD17B10STSLMNA | |
| SCHEMBL6656065 | 0.85 | STS (0.64) | GAAKMT2AHSD17B10STSLMNA | |
| SCHEMBL28095416 | 0.84 | MAPT (0.55) | GAAKMT2AHSD17B10STSLMNA | |
| SCHEMBL3762150 | 0.83 | RAB9A (0.55) | GAAKMT2AHSD17B10LMNAALDH1A1 | |
| SCHEMBL4230721 | 0.81 | RAB9A (0.53) | GAAKMT2AHSD17B10LMNAALDH1A1 | |
| SCHEMBL11764286 | 0.81 | CYP1A2 (0.64) | GAAKMT2AALDH1A1NPC1RAB9A | |
| Benzoic Acid SCHEMBL28087661 | 0.81 | MAPT (0.53) | GAAKMT2AHSD17B10LMNAALDH1A1 | |
| SCHEMBL29039855 | 0.81 | LMNA (0.63) | GAAKMT2AHSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |
| EP-0966424-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998032730-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-07-30 | — | — | WO | disclosed |