Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081775 | 0.78 | ALDH1A1 (0.38) | DHFRALDH1A1HPGDMAPTPOLB | |
| SCHEMBL4622945 | 0.78 | ALDH1A1 (0.38) | DHFRALDH1A1HPGDMAPTPOLB | |
| SCHEMBL714807 | 0.78 | ALDH1A1 (0.42) | DHFRENPP3ENPP1MAOAMAOB | |
| SCHEMBL6237071 | 0.77 | DHFR (0.40) | DHFRENPP3ENPP1ALOX15MAOA | |
| SCHEMBL8154866 | 0.74 | MAOA (0.39) | DHFRENPP3ENPP1MAOAMAOB | |
| SCHEMBL5599459 | 0.72 | DHFR (0.41) | DHFRENPP3ENPP1MAOAMAOB | |
| SCHEMBL7030492 | 0.69 | DHFR (0.38) | DHFRENPP3ENPP1MAOAMAOB | |
| SCHEMBL14600076 | 0.68 | ALDH1A1 (0.48) | ALOX15TDP1ALDH1A1HPGDTSHR | |
| SCHEMBL5691721 | 0.68 | DNMT1 (0.39) | DHFRMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL5689656 | 0.68 | KDM4E (0.38) | DHFRALOX15MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016019-A9 | METHOD FOR MEASURING THE LEVEL OF A MEDIUM IN A REACTOR | BASELL POLIOLEFINE SPA (IT) | 2004-05-13 | — | — | WO | disclosed |
| EP-1219657-A1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | Japan Science and Technology Corporation (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-1090049-A1 | PROPYLENE TERPOLYMERS WITH A LOW EXTRACTABLE PORTION | Basell Polyolefine GmbH (DE) | 2001-04-11 | — | — | EP | disclosed |
| EP-0968234-A1 | SUPPORTED CATALYST SYSTEM FOR POLYMERIZING ALK-1-ENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999067307-A1 | PROPYLENE TERPOLYMERS WITH A LOW EXTRACTABLE PORTION | TARGOR GMBH (DE) | 1999-12-29 | — | — | WO | disclosed |
| WO-1998040418-A1 | SUPPORTED CATALYST SYSTEM FOR POLYMERIZING ALK-1-ENES | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |