Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268123 | 0.86 | HSD17B10 (0.40) | ALDH1A1CYP2A6POLBKDM4EHPGD | |
| SCHEMBL7269629 | 0.84 | CES1 (0.36) | ALDH1A1CYP2A6POLBKDM4EGAA | |
| SCHEMBL4622945 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP2A6POLBDHFRHPGD | |
| SCHEMBL5081775 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP2A6POLBDHFRHPGD | |
| SCHEMBL6651463 | 0.78 | DHFR (0.38) | ALDH1A1CYP2A6POLBDHFRKDM4E | |
| SCHEMBL7269663 | 0.77 | TDP1 (0.37) | ALDH1A1CYP2A6POLBDHFRKDM4E | |
| SCHEMBL8154866 | 0.77 | MAOA (0.39) | ALDH1A1CYP2A6POLBDHFRKDM4E | |
| SCHEMBL5599459 | 0.75 | DHFR (0.41) | ALDH1A1CYP2A6POLBDHFRKDM4E | |
| SCHEMBL7262259 | 0.75 | TDP1 (0.36) | ALDH1A1CYP2A6POLBKDM4EGAA | |
| SCHEMBL218375 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CYP2A6POLBDHFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| EP-1501843-B1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-06-14 | — | — | EP | claimed |
| EP-0779295-B1 | Metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2004-10-20 | — | — | EP | claimed |
| EP-0779306-B1 | Process for preparation of cycloolefin copolymers | TICONA GMBH (DE) | 2003-12-03 | — | — | EP | claimed |
| EP-1328533-A1 | BRIDGED YLIDE GROUP CONTAINING METAL COMPLEXES | Dow Global Technologies Inc. (US) | 2003-07-23 | — | — | EP | claimed |
| US-6476283-B1 | Hydrogenation of unsaturated polymers using divalent diene-containing bis-cyclopentadienyl group IV metal catalysts | THE DOW CHEMICAL COMPANY | 2002-11-05 | — | — | US | claimed |
| WO-2002034759-A1 | BRIDGED YLIDE GROUP CONTAINING METAL COMPLEXES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-05-02 | — | — | WO | claimed |
| EP-1134227-A2 | Methylene-bridged biscyclopentadienyl compounds | Basell Polyolefine GmbH (DE) | 2001-09-19 | — | — | EP | claimed |
| US-6255508-B1 | COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | claimed |
| EP-0901497-B1 | YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW CHEMICAL CO (US) | 2001-01-10 | — | — | EP | claimed |
| US-6160065-A | Yttrium containing metal complexes and olefin polymerization process | THE DOW CHEMICAL COMPANY (US) | 2000-12-12 | — | — | US | claimed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | claimed |
| CN-1216548-A | Yttrium-containing metal complexes and olefin polymerization process | DOW CHEMICAL CO (US) | 1999-05-12 | — | — | CN | claimed |
| EP-0901497-A1 | YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-03-17 | — | — | EP | claimed |
| US-5808122-A | Organometallic compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | claimed |
| US-5726333-A | POLYMERIZATION CATALYSTS | HOECHST AG (DE) | 1998-03-10 | — | — | US | claimed |
| WO-1997043294-A1 | YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1997-11-20 | — | — | WO | claimed |
| EP-3587457-B1 | METHOD OF TRANSFERRING SLURRY AND METHOD OF PRODUCING POLYOLEFIN | SUMITOMO CHEMICAL CO (JP) | 2023-09-27 | — | — | EP | disclosed |
| EP-0654476-A1 | Metallocenes, their preparation and use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-24 | — | — | EP | disclosed |