Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753712 | 0.88 | CYP4F2 (0.44) | DGKAEPHX2NLRP3ALDH1A1TDP1 | |
| SCHEMBL11805792 | 0.88 | DGKA (0.49) | DGKAEPHX2DNM1NLRP3PRSS1 | |
| SCHEMBL2720980 | 0.83 | HPGD (0.41) | EPHX2ALDH1A1TDP1KMT2A | |
| SCHEMBL14460742 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TDP1KMT2ACNR2MAPT | |
| SCHEMBL14460014 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TDP1KMT2ACNR2MAPT | |
| SCHEMBL9277242 | 0.82 | DGKA (0.43) | DGKAEPHX2DNM1NLRP3PRSS1 | |
| SCHEMBL9496137 | 0.81 | TSHR (0.40) | EPHX2ALDH1A1TDP1MAPT | |
| SCHEMBL10626171 | 0.79 | PPARG (0.35) | ALDH1A1KDM4E | |
| SCHEMBL4978611 | 0.79 | DGKA (0.40) | DGKAEPHX2DNM1NLRP3ALDH1A1 | |
| SCHEMBL11103925 | 0.77 | DGKA (0.51) | DGKAEPHX2DNM1NLRP3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5213862-A | — | — | None | — | — | JP | disclosed |
| EP-0695741-B1 | 7-THIAPROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-5731452-A | 7-thiaprostaglandins and method of production thereof | TEIJIN LIMITED (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0695741-A1 | 7-THIAPROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-02-07 | — | — | EP | disclosed |
| JP-H05213862-A | PROSTAGLANDIN ANALOG | MIZUSHIMA YUTAKA | 1993-08-24 | — | — | JP | disclosed |