SCHEMBL6652271

SCHEMBL6652271

CC1=Cc2c(cccc2-c2ccccc2C)[CH]1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
ALDH1A1 P00352 3/20 0.33
BRD4 O60885 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KIF11 P52732 1/20 0.32
HTR1A P08908 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2D6 P10635 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4333409 0.81 CYP2A6 (0.36) TSHRACHEALDH1A1CYP1A2CYP2A6
SCHEMBL60836 0.81 PDCD1 (0.39) TSHRACHEALDH1A1HPGDCYP1A2
SCHEMBL714806 0.80 ALDH1A1 (0.39) TSHRALDH1A1HPGDCYP1A2HSD17B10
SCHEMBL29174107 0.79 CYP2A6 (0.35) TSHRACHEALDH1A1CYP1A2CYP2A6
SCHEMBL20548534 0.79 PDCD1 (0.38) TSHRACHEALDH1A1HPGDCYP1A2
SCHEMBL5721167 0.78 HEXA (0.34) NPC1RAB9ASMN1; SMN2CASP3SENP8
SCHEMBL3064332 0.78 DCUN1D1 (0.40) HTR7NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7624416 0.77 ADORA3 (0.38) NPC1RAB9ASMN1; SMN2ACHEHPGD
SCHEMBL7268119 0.76 HPRT1 (0.44) RAB9ATSHRALDH1A1HPGDCYP1A2
SCHEMBL6046805 0.76 ALDH1A1 (0.42) TSHRACHEALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105358562-A Racemo selective metallation process EXXONMOBIL CHEM PATENTS INC 2016-02-24 CN claimed
US-20040010102-A1 Bridged ylide group containning metal complexes ROBERT BOSCH GMBH (DE) 2004-01-15 US claimed
EP-1328533-A1 BRIDGED YLIDE GROUP CONTAINING METAL COMPLEXES Dow Global Technologies Inc. (US) 2003-07-23 EP claimed
US-6500949-B2 ALPHA-OLEFIN POLYMERIZATION CATALYST DOW GLOBAL TECHNOLOGIES INC. 2002-12-31 US claimed
US-6476283-B1 Hydrogenation of unsaturated polymers using divalent diene-containing bis-cyclopentadienyl group IV metal catalysts THE DOW CHEMICAL COMPANY 2002-11-05 US claimed
WO-2002034759-A1 BRIDGED YLIDE GROUP CONTAINING METAL COMPLEXES DOW GLOBAL TECHNOLOGIES INC. (US) 2002-05-02 WO claimed
US-20010025115-A1 Bridged metal complexes DOW GLOBAL TECHNOLOGIES LLC 2001-09-27 US claimed
CN-105358562-A Racemo selective metallation process EXXONMOBIL CHEM PATENTS INC 2016-02-24 CN disclosed
WO-2013158411-A1 METHODS OF SEPARATING COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-24 WO disclosed
US-20130276519-A1 Methods of Separating Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2013-10-24 US disclosed
CN-1258562-C Resin composition and its use MITSUI CHEMICALS INC (JP) 2006-06-07 CN disclosed
CN-1258561-C Resin composition and its use MITSUI CHEMICALS INC (JP) 2006-06-07 CN disclosed
CN-1169900-C Adhesive resin composition and laminate made using same as adhesive layer ������ѧ��ʽ���� 2004-10-06 CN disclosed
CN-1216057-A Adhesive resin composition and laminate using the same as adhesive layer MITSUI CHEMICALS INC (JP) 1999-05-05 CN disclosed
CN-1208050-A Olefin thermoplastic elastomer composition MITSUI CHEMICALS INC (JP) 1999-02-17 CN disclosed
CN-1206026-A Unsaturated elastomer compositions and their vulcanized MITSUI CHEMICALS INC (JP) 1999-01-27 CN disclosed
CN-1165529-A Resin composition and use thereof MITSUI PETROCHEMICAL IND (JP) 1997-11-19 CN disclosed
CN-1141320-A Polyamide resin composition MITSUI PETROCHEMICAL IND (JP) 1997-01-29 CN disclosed
CN-1140728-A Olefinic thermoplastic elastomer composition MITSUI PETROCHEMICAL IND (JP) 1997-01-22 CN disclosed
CN-1139676-A Ethylene copolymer rubber, sulphurable rubber combination containing copolymer rubber and preparation process for same MITSUI PETROCHEMICAL IND (JP) 1997-01-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010025115-A1 Bridged metal complexes SLC39A14, NBAS, MCM4 HTR7 4460/4885NPC1 2548/4885RAB9A 1811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.