SCHEMBL6652280

SCHEMBL6652280

CCO[SiH](CCCCN)OCC.CO[SiH](CCCCN)OC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37812 0.91 DNM1 (0.38) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL483769 0.89 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL964816 0.89 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL483441 0.89 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL452818 0.89 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL28563615 0.89 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL8022696 0.89
SCHEMBL28182730 0.87 CYP1A2 (0.30)
SCHEMBL8019425 0.87
SCHEMBL37576 0.87 NFKB1 (0.39) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392460-A1 HYDROGENFLUORIDES OF AMINOSILANOLS AND THEIR USE ASHLAND INC. (US) 2004-03-03 EP disclosed
US-6664310-B2 Foundry binder ASHLAND INC. 2003-12-16 US disclosed
US-6632856-B2 A no-bake foundry binder system comprising: (a) polyether polyol component comprising, (1) a polyether polyol, (2) a fluorinated acid (3) an aminoalkoxysilane, (b) a polyisocyanate component, (C) a liquid tertiary amine catalyst ASK Chemicals LLC 2003-10-14 US disclosed
US-6602931-B2 Polyurethane-forming binders ASHLAND INC. 2003-08-05 US disclosed
US-20030042000-A1 Polyurethane-forming binders ASK Chemicals LLC 2003-03-06 US disclosed
US-20030037904-A1 A no-bake foundry binder system comprising: (a) polyether polyol component comprising, (1) a polyether polyol, (2) a fluorinated acid (3) an aminoalkoxysilane, (b) a polyisocyanate component, (C) a liquid tertiary amine catalyst ASK Chemicals LLC 2003-02-27 US disclosed
WO-2003009954-A1 POLYURETHANE-FORMING BINDERS ASHLAND INC. (US) 2003-02-06 WO disclosed
US-20030004224-A1 Hydrogenfluorides of aminosilanols and their use ASK Chemicals LLC 2003-01-02 US disclosed
WO-2002090016-A1 HYDROGENFLUORIDES OF AMINOSILANOLS AND THEIR USE ASHLAND INC. (US) 2002-11-14 WO disclosed
US-6013372-A SELF-CLEANING, WEAR RESISTANT COATING TOTO, LTD. (JP) 2000-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030004224-A1 Hydrogenfluorides of aminosilanols and their use HSF1, HSPBP1, BAG3 DNM1 3864/4885MEN1 1023/4885KMT2A 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.