Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540135 | 0.75 | RECQL (0.38) | — | |
| SCHEMBL5873715 | 0.69 | — | — | |
| SCHEMBL9557367 | 0.68 | MKNK1 (0.45) | CDC7MKNK1 | |
| Hydrochloric Acid SCHEMBL947630 | 0.68 | — | — | |
| SCHEMBL5173417 | 0.68 | — | — | |
| SCHEMBL29597773 | 0.68 | — | — | |
| SCHEMBL16619921 | 0.67 | CAMKK2 (0.35) | HSP90AA1CAMKK2ROCK1CDC42BPB | |
| SCHEMBL3332784 | 0.66 | CHRNB2 (0.49) | — | |
| SCHEMBL20577257 | 0.66 | HTR3A (0.41) | MKNK1ROCK1CDC42BPB | |
| SCHEMBL20577255 | 0.66 | HTR3A (0.41) | MKNK1ROCK1CDC42BPB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883928-A1 | GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-1389194-A2 | INHIBITORS OF BACE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002088101-A2 | INHIBITORS OF BACE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2002-11-07 | — | — | WO | disclosed |