Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363316 | 0.81 | TDP1 (0.48) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL10353222 | 0.79 | TDP1 (0.47) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL3259340 | 0.79 | CES2 (0.41) | CES2CES1LMNACA2CA4 | |
| SCHEMBL11398006 | 0.78 | PARP1 (0.49) | TDP1TSHRMEN1NPC1POLB | |
| SCHEMBL23706328 | 0.78 | TDP1 (0.45) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL4873699 | 0.78 | TDP1 (0.45) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL10580248 | 0.78 | TDP1 (0.45) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL571674 | 0.78 | TDP1 (0.45) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL6081855 | 0.78 | PGR (0.46) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL599311 | 0.78 | TDP1 (0.45) | CES2CES1LMNATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109320488-A | A kind of water phase one-pot synthesis method of 3-hydroxyflavone and its derivative | 中国科学院成都生物研究所 | 2019-02-12 | — | — | CN | disclosed |
| CN-1179956-C | Intermediate for preparing substituted dioxazine | — | 2004-12-15 | — | — | CN | disclosed |
| EP-0846691-B1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER CROPSCIENCE AG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6437153-B1 | O-HYDROXYETHYL-O'-ALKYLBENZOFURANDIONE DIOXIMES REARRANGED IN THE PRESENCE OF A DILENT, AN ACID OR A BASE; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-04-25 | — | — | US | disclosed |
| CN-1082955-C | Process for preparing 3- (1-hydroxyphenyl-1-alkoxyiminomethyl) dioxazines | BAYER AG (DE) | 2002-04-17 | — | — | CN | disclosed |
| US-6335454-B1 | FUNGICIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| CN-1313283-A | Intermediate for preparing substituted dioxazine | BAYER AG (DE) | 2001-09-19 | — | — | CN | disclosed |
| US-6093837-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-25 | — | — | US | disclosed |
| US-6005104-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES; PREPARED BY REARRANGING O-HYDROXYETHYL-O'-ALKYL-BENZOFURANDIONE DIOXIMES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| CN-1184811-A | Process for preparing 3- (1-hydroxyphenyl-1-alkoxyiminomethyl) dioxazines | BAYER AG (DE) | 1998-06-17 | — | — | CN | disclosed |
| EP-0846691-A1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER AG (DE) | 1998-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | DDT, CYP4Z1, CYP51A1 | CES2 382/4885CES1 1178/4885LMNA 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.