Sugi Predict

Sugi Predict / Compounds / SCHEMBL571674

SCHEMBL571674

SCHEMBL571674

O=C(c1ccccc1)C(Br)[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ CES2 O00748 5/20 0.44
▸ CES1 P23141 5/20 0.44
▸ LMNA P02545 1/20 0.44
▸ CYP1A2 P05177 1/20 0.42
▸ MDM2 Q00987 1/20 0.41
▸ CA2 P00918 1/20 0.40
▸ CA4 P22748 1/20 0.40
▸ DAO P14920 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ NAPRT Q6XQN6 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ PRMT1 Q99873 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ MITF O75030 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8107700 0.84 TDP1 (0.41) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL10353222 0.82 TDP1 (0.47) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL4363316 0.79 TDP1 (0.48) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL28231951 0.79 NR4A1 (0.57) LMNACYP1A2ALDH1A1MEN1RAB9A
SCHEMBL6652948 0.78 CES2 (0.50) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL23706328 0.76 TDP1 (0.45) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL10580248 0.76 TDP1 (0.45) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL4873699 0.76 TDP1 (0.45) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL599311 0.76 TDP1 (0.45) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL6081855 0.76 PGR (0.46) TDP1L3MBTL1CES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036642-A Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof 江西农业大学 2026-05-15 — — CN claimed
CN-116769741-B Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone 河北牧群生物科技有限公司 2024-06-18 — — CN claimed
CN-116769741-A Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone 河北牧群生物科技有限公司 2023-09-19 — — CN claimed
CN-113880786-A Synthesis method and antioxidant application of camphene aldehyde thiazole hydrazone derivative 江西农业大学 2022-01-04 — — CN claimed
CN-109096339-B Preparation of terpyridyl ruthenium complex and application of terpyridyl ruthenium complex in reverse transcriptase inhibition 云南大学 2020-10-02 — — CN claimed
CN-109096339-A A kind of preparation of terpyridyl ruthenium complex and the application in reverse transcriptase inhibition 云南大学 2018-12-28 — — CN claimed
CN-108676016-A A kind of synthetic method of myrte base imidazo [2,1-b] [1,3,4] thiadiazole compound 广西大学 2018-10-19 — — CN claimed
CN-103627776-A Method for preparing S-2-(4-nitrobenzophenone) oxirane UNIV JIANGNAN 2014-03-12 — — CN claimed
JP-56123950-A — — None — — JP disclosed
CN-122036642-A Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof 江西农业大学 2026-05-15 — — CN disclosed
CN-116769741-B Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone 河北牧群生物科技有限公司 2024-06-18 — — CN disclosed
CN-116769741-A Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone 河北牧群生物科技有限公司 2023-09-19 — — CN disclosed
CN-113880786-B Synthesis method and anti-oxidation application of camphene aldehyde thiazole hydrazone derivative 江西农业大学 2023-03-03 — — CN disclosed
US-11582970-B2 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth NORTH CAROLINA STATE UNIVERSITY (US) 2023-02-21 — — US disclosed
WO-1997026300-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1997-07-24 — — WO disclosed
US-5155268-A Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides THE UPJOHN COMPANY (US) 1992-10-13 — — US disclosed
CN-1049659-A Curative BOOTS CO PLC (GB) 1991-03-06 — — CN disclosed
EP-0164865-B1 N-(AMINOALKYLPHENYL)SULFONAMIDES THEIR PREPARATION AND THERAPEUTIC USE THE UPJOHN COMPANY (US) 1988-12-21 — — EP disclosed
EP-0164865-A1 N-(Aminoalkylphenyl)sulfonamides their preparation and therapeutic use THE UPJOHN COMPANY (US) 1985-12-18 — — EP disclosed
JP-S56123950-A PREPARATION OF M-NITRO-OMEGA-BROMOACETOPHENONE PAAMAKEMU ASIA:KK 1981-09-29 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11582970-B2 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth DDC, IL4I1, ING2 TDP1 3958/4885L3MBTL1 3259/4885CES2 3185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.