Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22319938 | 0.84 | AR (0.43) | ARPGR | |
| SCHEMBL6348407 | 0.79 | AR (0.42) | ARPGR | |
| SCHEMBL11364366 | 0.77 | PTGS1 (0.46) | ARPGR | |
| SCHEMBL13141384 | 0.75 | AR (0.42) | ARPGR | |
| SCHEMBL22366377 | 0.74 | ALDH1A1 (0.43) | ARPGR | |
| SCHEMBL11380054 | 0.74 | HPGD (0.46) | ARPGR | |
| SCHEMBL7759328 | 0.73 | KDM4E (0.47) | AR | |
| SCHEMBL5158088 | 0.73 | — | — | |
| SCHEMBL22319850 | 0.69 | CYP4F2 (0.44) | ARPGR | |
| SCHEMBL12820842 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956294-B1 | THROMBIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6740647-B1 | AMIDINES AND HYDROXYAMIDINE DERIVATIVES | ABBOTT GMBH & CO., KG (DE) | 2004-05-25 | — | — | US | disclosed |
| CN-1289341-A | Thrombin inhibitors | BASF AG (DE) | 2001-03-28 | — | — | CN | disclosed |
| US-6114358-A | Thrombin inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| CN-1228783-A | Novel thrombin inhibitors | BASF AG (DE) | 1999-09-15 | — | — | CN | disclosed |