Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653296 | 0.79 | AR (0.46) | ARPGR | |
| SCHEMBL13141384 | 0.79 | AR (0.42) | ARPGR | |
| SCHEMBL22319938 | 0.76 | AR (0.43) | ARPGR | |
| SCHEMBL11364366 | 0.73 | PTGS1 (0.46) | ARPGR | |
| SCHEMBL4275644 | 0.71 | — | — | |
| SCHEMBL11380054 | 0.71 | HPGD (0.46) | ARPGR | |
| SCHEMBL22366377 | 0.71 | ALDH1A1 (0.43) | ARPGR | |
| SCHEMBL241343 | 0.69 | — | — | |
| SCHEMBL2955486 | 0.69 | — | — | |
| SCHEMBL5158088 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864249-B2 | Pharmaceutical compositions containing them are of the class of thrombin inhibitors which are useful as anticoagulants. | LG LIFE SCIENCES, LTD. (KR) | 2005-03-08 | — | — | US | disclosed |
| EP-1140918-B1 | THROMBIN INHIBITORS | LG LIFE SCIENCES LTD (KR) | 2004-08-11 | — | — | EP | disclosed |
| EP-0956294-B1 | THROMBIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6740647-B1 | AMIDINES AND HYDROXYAMIDINE DERIVATIVES | ABBOTT GMBH & CO., KG (DE) | 2004-05-25 | — | — | US | disclosed |
| CN-1149210-C | Thrombin inhibitors | ��ʽ����LG������ѧ | 2004-05-12 | — | — | CN | disclosed |
| US-20030134801-A1 | Pharmaceutical compositions containing them are of the class of thrombin inhibitors which are useful as anticoagulants. | LG LIFE SCIENCES, LTD. | 2003-07-17 | — | — | US | disclosed |
| US-6492402-B1 | ANTICOAGULANTS; PEPTIDE DERIVATIVES HAVING HIGH ANTITHROMBOTIC ACTIVITY AND ORAL BIOAVAILABILITY | LG LIFE SCIENCES, LTD. (KR) | 2002-12-10 | — | — | US | disclosed |
| CN-1332737-A | Thrombin inhibitors | LG CI LTD (KR) | 2002-01-23 | — | — | CN | disclosed |
| EP-1140918-A1 | THROMBIN INHIBITORS | LG CI Ltd. (KR) | 2001-10-10 | — | — | EP | disclosed |
| US-6114358-A | Thrombin inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-2000039124-A1 | THROMBIN INHIBITORS | LG CI LTD. (KR) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134801-A1 | Pharmaceutical compositions containing them are of the class of thrombin inhibitors which are useful as anticoagulants. | SERPINC1, F2, F12 | AR 4676/4885PGR 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.