Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029355 | 0.89 | MAPT (0.36) | MAOAKDM4EMAPTATRALDH1A1 | |
| Tetrahydrofuran SCHEMBL6653304 | 0.85 | MAOA (0.41) | MAOAPDE3BPDE3AMEN1POLB | |
| SCHEMBL4387010 | 0.80 | MAOA (0.46) | MAOAPDE3BPDE3AKDM4ECA12 | |
| SCHEMBL1354385 | 0.79 | MAOA (0.50) | MAOAPDE3BPDE3AMTORKDM4E | |
| Hydrochloric Acid SCHEMBL2385610 | 0.77 | MAOA (0.49) | MAOAPDE3BPDE3AMTORKDM4E | |
| SCHEMBL21662565 | 0.74 | MAPT (0.33) | MAOAMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL13515431 | 0.73 | MEN1 (0.39) | MEN1POLBKMT2AKDM4EMAPT | |
| SCHEMBL238377 | 0.71 | ALDH1A1 (0.43) | MEN1POLBKMT2AKDM4ECA12 | |
| SCHEMBL28980419 | 0.70 | MAPT (0.35) | MAOAMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL21634758 | 0.70 | LRRK2 (0.35) | MAOAMAPTALDH1A1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451164-A2 | AMIDE DERIVATIVES HAVING IMPROVED SOLUBILITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003006440-A2 | AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |