Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.31 |
| ▸ | FEN1 | P39748 | 3/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL6653299 | 0.89 | MAOA (0.39) | MAPTKDM4EATRALDH1A1MAOA | |
| SCHEMBL13515431 | 0.81 | MEN1 (0.39) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21662565 | 0.80 | MAPT (0.33) | MAPTALDH1A1MAOASMN1; SMN2LMNA | |
| SCHEMBL28980419 | 0.79 | MAPT (0.35) | MAPTALDH1A1MAOASMN1; SMN2LMNA | |
| SCHEMBL21634758 | 0.78 | LRRK2 (0.35) | MAPTALDH1A1MAOASMN1; SMN2LRRK2 | |
| SCHEMBL22689408 | 0.78 | SLC6A9 (0.32) | MAOAALOX5AP | |
| SCHEMBL30199085 | 0.77 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2255157 | 0.77 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21634788 | 0.77 | MAOA (0.32) | MAPTMAOA | |
| SCHEMBL3038716 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774231-B2 | BACTERICIDES | PHARMACIA & UPJOHN COMPANY | 2004-08-10 | — | — | US | claimed |
| EP-4568961-A1 | PROCESSES FOR PREPARING OXAZOLIDINONE COMPOUNDS | Merck Sharp & Dohme LLC (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035618-A1 | PROCESSES FOR PREPARING OXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2024-02-15 | — | — | WO | disclosed |
| WO-2024035618-A1 | PROCESSES FOR PREPARING OXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2024-02-15 | — | — | WO | disclosed |
| US-7645781-B2 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PFIZER INC (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645781-B2 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PFIZER INC (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645781-B2 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PFIZER INC (US) | 2010-01-12 | — | — | US | disclosed |
| US-20070015801-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | THOMAS RICHARD C | 2007-01-18 | — | — | US | disclosed |
| US-20070015801-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | THOMAS RICHARD C | 2007-01-18 | — | — | US | disclosed |
| US-20070015801-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | THOMAS RICHARD C | 2007-01-18 | — | — | US | disclosed |
| US-20040147760-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-29 | — | — | US | disclosed |
| US-20040044052-A1 | N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives | PHARMACIA & UPJOHN COMPANY | 2004-03-04 | — | — | US | disclosed |
| US-20040014967-A1 | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound | PHARMACIA & UPJOHN COMPANY | 2004-01-22 | — | — | US | disclosed |
| WO-2003072553-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
| US-6605609-B2 | N-(((5S)-3-(4-(1,1-dioxido-4-thiomorpholinyl)-3,5-difluorophen yl) -2-oxo-1,3-oxazolidin-5-yl)methyl)acetamide antimicrobial used in combination therapy | PHARMACIA & UPJOHN COMPANY | 2003-08-12 | — | — | US | disclosed |
| EP-1294717-A2 | A THIAZINE OXAZOLIDINONE | PHARMACIA & UPJOHN COMPANY (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2003006440-A2 | AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |
| US-20030004160-A1 | Method for the preparation of oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2003-01-02 | — | — | US | disclosed |
| US-20020156072-A1 | Thiazine oxazolidinone | PHARMACIA & UPJOHN COMPANY | 2002-10-24 | — | — | US | disclosed |
| WO-2001098297-A2 | A THIAZINE OXAZOLIDINONE | PHARMACIA & UP JOHN COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156072-A1 | Thiazine oxazolidinone | OXA1L, TLR5, TALDO1 | MAPT 4319/4885KDM4E 4350/4885ATR 2595/4885 |
| US-20040147760-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | OXA1L, AADAC, MT-ND5 | MAPT 4491/4885KDM4E 905/4885ATR 3427/4885 |
| US-20040044052-A1 | N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives | OXA1L, AADAC, MT-ND5 | MAPT 4491/4885KDM4E 905/4885ATR 3427/4885 |
| US-20030004160-A1 | Method for the preparation of oxazolidinones | CYP3A5, OXA1L, OGFOD1 | MAPT 3208/4885KDM4E 2833/4885ATR 4244/4885 |
| US-20040014967-A1 | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound | AADAC, AAAS, SLC7A1 | MAPT 1484/4885KDM4E 971/4885ATR 1251/4885 |
| US-20070015801-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | OXA1L, AADAC, MT-ND5 | MAPT 4491/4885KDM4E 905/4885ATR 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.