Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655399 | 0.98 | GFER (0.61) | GFERSMN1; SMN2POLBTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL6653320 | 0.97 | GFER (0.60) | GFERSMN1; SMN2POLBTSHRALDH1A1 | |
| Hypochlorous Acid SCHEMBL6652746 | 0.83 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL13149394 | 0.82 | ALDH1A1 (0.77) | GFERSMN1; SMN2POLBTSHRALDH1A1 | |
| SCHEMBL6650909 | 0.81 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1LMNAHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL6652741 | 0.80 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL6660079 | 0.78 | HCRTR1 (0.45) | TSHRALDH1A1LMNAHSD17B10KDM4E | |
| Hypochlorous Acid SCHEMBL6652392 | 0.76 | HCRTR1 (0.44) | ALDH1A1LMNAKDM4EHPGDMEN1 | |
| Hypochlorous Acid SCHEMBL6650991 | 0.76 | HCRTR1 (0.48) | SMN1; SMN2ALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL6651379 | 0.76 | ACHE (0.53) | MEN1KMT2AHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | claimed |
| US-6372746-B1 | ANTICONVULSIVE AGENTS, SEDATIVES AND EATING DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-04-16 | — | — | US | claimed |
| EP-1006110-A1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-06-07 | — | — | EP | claimed |