Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651413 | 0.84 | TP53 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL6652771 | 0.84 | ALDH1A1 (0.57) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL6653359 | 0.83 | ALDH1A1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL6655484 | 0.83 | SLC6A7 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL6652784 | 0.81 | HCRTR1 (0.55) | HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL6653362 | 0.81 | ALDH1A1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL6652211 | 0.81 | SLC6A7 (0.62) | MEN1KMT2A | |
| SCHEMBL6674771 | 0.81 | L3MBTL1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL6652154 | 0.81 | L3MBTL1 (0.67) | HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL28019839 | 0.80 | OGA (0.51) | ACHEOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202087-C | Derivatives of acyl-piperazinil-pyrimidins, preparation thereof and application as medicaments | ESTEVE LABOR DR (ES) | 2005-05-18 | — | — | CN | claimed |
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | claimed |
| US-6372746-B1 | ANTICONVULSIVE AGENTS, SEDATIVES AND EATING DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-04-16 | — | — | US | claimed |
| CN-1268124-A | Acyl-piperazinyl-pyrimidine derivatives, their preparation and use as medicaments | ESTEVE LABOR DR (ES) | 2000-09-27 | — | — | CN | claimed |
| EP-1006110-A1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-06-07 | — | — | EP | claimed |