Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019328 | 0.80 | CA2 (0.61) | SMN1; SMN2KMT2AALDH1A1ATML3MBTL1 | |
| SCHEMBL29183283 | 0.77 | ALDH1A1 (0.55) | ALDH1A1ATML3MBTL1 | |
| SCHEMBL27920887 | 0.75 | POLB (0.43) | SMN1; SMN2ALDH1A1ATML3MBTL1CA2 | |
| SCHEMBL9765296 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2AALDH1A1ATML3MBTL1 | |
| SCHEMBL11703554 | 0.72 | ALDH1A1 (0.60) | SMN1; SMN2KMT2AALDH1A1ATML3MBTL1 | |
| SCHEMBL8548241 | 0.72 | KMT2A (0.78) | FBP1SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL171036 | 0.71 | KMT2A (0.61) | FBP1SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL11706540 | 0.71 | KMT2A (0.76) | FBP1SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL9462804 | 0.70 | SMN1; SMN2 (0.81) | SMN1; SMN2KMT2AALDH1A1CA12CA2 | |
| SCHEMBL2733961 | 0.70 | FBP1 (0.46) | FBP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442027-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003031419-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-17 | — | — | WO | disclosed |