SCHEMBL29183283

SCHEMBL29183283

CCCCC(NS(=O)(=O)c1ccc(OC)cc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
POLB P06746 2/20 0.55
MMP13 P45452 3/20 0.51
HSD17B10 Q99714 1/20 0.51
KCNA5 P22460 1/20 0.51
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HDAC1 Q13547 1/20 0.48
MMP9 P14780 1/20 0.48
BMP1 P13497 2/20 0.48
PKM P14618 1/20 0.47
HTR7 P34969 1/20 0.47
KDM4E B2RXH2 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
CNR1 P21554 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765306 0.81 KCNA5 (0.55) ALDH1A1POLBKCNA5ATML3MBTL1
SCHEMBL9765264 0.81 KCNA5 (0.55) ALDH1A1POLBKCNA5ATML3MBTL1
SCHEMBL29207034 0.80 ALDH1A1 (0.65) ALDH1A1POLBMMP13HSD17B10MMP9
SCHEMBL8894902 0.79 HSD17B10 (0.49) ALDH1A1POLBMMP13HSD17B10ATM
SCHEMBL28617908 0.78 ALDH1A1 (0.67) ALDH1A1POLBHSD17B10MMP9CYP2C19
SCHEMBL29163156 0.78 MMP2 (0.58) MMP13HSD17B10MMP9
SCHEMBL29183281 0.78 MMP2 (0.58) MMP13HSD17B10MMP9
SCHEMBL7410702 0.78 PDE4A (0.67) ALDH1A1POLBKCNA5ATML3MBTL1
SCHEMBL8895359 0.77 HSD17B10 (0.49) ALDH1A1POLBMMP13HSD17B10HDAC1
SCHEMBL6653350 0.77 FBP1 (0.49) ALDH1A1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658945-A Synthesis method of persulfate-induced alkylation modified nitrogen heterocyclic compound 浙江工业大学 2024-03-08 CN disclosed
CN-117645581-A Method for synthesizing series of functional groups of photocatalytic inert C (sp 3) -H bond 浙江工业大学台州研究院 2024-03-05 CN disclosed