Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235913 | 0.78 | PTPN1 (0.41) | L3MBTL1ALDH1A1KDM4EPTPN1CYP1A2 | |
| SCHEMBL2310858 | 0.75 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1KDM4EPTPN1CYP1A2 | |
| SCHEMBL7059040 | 0.72 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1KDM4EPTPN1CYP1A2 | |
| SCHEMBL3082564 | 0.71 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1PTPN1CYP1A2LMNA | |
| SCHEMBL2864614 | 0.69 | PRKCA (0.40) | L3MBTL1ALDH1A1PTPN1CYP1A2LMNA | |
| SCHEMBL3082671 | 0.67 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4EPTPN1CYP1A2 | |
| SCHEMBL18098832 | 0.66 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1KDM4EPTPN1CYP1A2 | |
| SCHEMBL5171537 | 0.66 | PTPN1 (0.45) | L3MBTL1ALDH1A1PTPN1CYP1A2LMNA | |
| SCHEMBL11194233 | 0.66 | PRKCA (0.38) | PTPN1ACP1CDC25B | |
| SCHEMBL20786806 | 0.65 | PTPN1 (0.46) | L3MBTL1ALDH1A1PTPN1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | disclosed |