Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864614 | 0.93 | PRKCA (0.40) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL2310858 | 0.88 | ALDH1A1 (0.41) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL11194233 | 0.88 | PRKCA (0.38) | PTPN1ACP1CDC25BPRKCA | |
| SCHEMBL20786806 | 0.82 | PTPN1 (0.46) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL16235913 | 0.79 | PTPN1 (0.41) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL3082564 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL6653740 | 0.72 | L3MBTL1 (0.39) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL11744307 | 0.69 | LMNA (0.34) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL5171537 | 0.68 | PTPN1 (0.45) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL24417054 | 0.66 | ALDH1A1 (0.55) | ALDH1A1CYP1A2LMNASMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035616-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |