Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24374911 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPK1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL29618548 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPK1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL15650364 | 0.82 | NOS3 (0.43) | ALDH1A1MAPK1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL10622006 | 0.77 | GBA1 (0.62) | ALDH1A1MAPK1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL13942706 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL30565568 | 0.76 | NOS3 (0.50) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL1097471 | 0.76 | NOS3 (0.50) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL23107378 | 0.75 | HSD17B10 (0.36) | ALDH1A1MAPK1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL23634062 | 0.75 | NOS2 (0.45) | ALDH1A1MAPK1CYP3A4TDP1NOS3 | |
| SCHEMBL21209067 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423368-A1 | UREA AND THIOUREA DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2004-06-02 | — | — | EP | disclosed |
| US-6610714-B2 | HIV viricides | MEDIVIR AB (SE) | 2003-08-26 | — | — | US | disclosed |
| US-20030092743-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2003-05-15 | — | — | US | disclosed |
| WO-2003020705-A1 | UREA AND THIOUREA DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2003-03-13 | — | — | WO | disclosed |
| US-5186717-A | Colorfastness, hair dyes | L'OREAL (FR) | 1993-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092743-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | SUB1, HCFC1, CCR1 | ALDH1A1 848/4885MAPK1 1395/4885L3MBTL1 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.