SCHEMBL6654429

SCHEMBL6654429

Cc1cc(C)c(S(OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
NR3C1 P04150 3/20 0.35
PGR P06401 3/20 0.35
NR3C2 P08235 3/20 0.35
METAP2 P50579 1/20 0.34
ABCC9 O60706 1/20 0.34
ABCC8 Q09428 1/20 0.34
KCNJ11 Q14654 1/20 0.34
KCNJ8 Q15842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
TSHR P16473 3/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
HTT P42858 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4961881 0.85 CA2 (0.42) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL4965786 0.85 CA2 (0.42) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL4964420 0.84 CA1 (0.45) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL4962467 0.84 CA1 (0.45) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL4962506 0.84 CA1 (0.45) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL4962907 0.84 CA1 (0.45) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL1573977 0.83 CA1 (0.43) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL4964033 0.80 HDAC1 (0.39) CA1CA2ABCC9ABCC8KCNJ11
SCHEMBL4964247 0.79 CA2 (0.46) CA1CA2KMT2AMEN1MAPT
SCHEMBL545781 0.78 HSD11B1 (0.38) CA1CA2ABCC9ABCC8KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US claimed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP claimed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP claimed
EP-1434091-A1 CHEMICAL-AMPLIFICATION-TYPE POSITIVE RADIATION-SENSITIVE RESIN COMPOSITION Clariant International Ltd. (CH) 2004-06-30 EP disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
US-20040033438-A1 Chemical-amplication-type positive radiation-sensitive resin composition AZ ELECTRONIC MATERIALS USA CORP. 2004-02-19 US disclosed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed