Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370889 | 0.87 | MTNR1A (0.54) | MTNR1AMTNR1BGLSMEN1KMT2A | |
| SCHEMBL11489742 | 0.84 | MMP8 (0.54) | MMP8CASRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4768337 | 0.84 | MMP8 (0.48) | MMP8CASRGAASMN1; SMN2MAPT | |
| SCHEMBL1824335 | 0.83 | SMN1; SMN2 (0.44) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL11494074 | 0.83 | MMP8 (0.53) | MMP8CASRGAASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL7137164 | 0.82 | MMP2 (0.47) | MMP8CASRGAASMN1; SMN2MAPT | |
| SCHEMBL28580536 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BMMP8CASRSMN1; SMN2 | |
| SCHEMBL640978 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BGLSSMN1; SMN2 | |
| SCHEMBL5435795 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BGLSSMN1; SMN2 | |
| SCHEMBL7310621 | 0.81 | HSD17B10 (0.59) | SMN1; SMN2MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186314-A1 | Process for the preparation of enantiomerically enriched n-acyl-beta-amino acid derivatives by enantioselective hydrogenation of the corresponding (z)-enamides | MALAN CHRISTOPHE GUILLAUME (CH) | 2004-09-23 | — | — | US | disclosed |
| EP-1421059-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED N-ACYL-BETA-AMINO ACID DERIVATIVES BY ENANTIOSELECTIVE HYDROGENATION OF THE CORRESPONDING (Z)-ENAMIDES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003016264-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED N-ACYL-BETA-AMINO ACID DERIVATIVES BY ENANTIOSELECTIVE HYDROGENATION OF THE CORRESPONDING (Z)-ENAMIDES | CHIROTECH TECHNOLOGY LIMITED (GB) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186314-A1 | Process for the preparation of enantiomerically enriched n-acyl-beta-amino acid derivatives by enantioselective hydrogenation of the corresponding (z)-enamides | EEF1D, ADH5, HRH3 | MTNR1A 2147/4885MTNR1B 2480/4885MMP8 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.