Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.59 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.59 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910196 | 0.91 | CACNA2D1 (0.50) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL1410027 | 0.87 | CACNA2D1 (0.74) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL665175 | 0.86 | CACNA2D1 (0.57) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL4194017 | 0.86 | CACNA2D1 (0.57) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL664788 | 0.86 | CACNA2D1 (0.57) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL13990312 | 0.84 | CACNA2D1 (0.55) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL4890230 | 0.82 | CACNA2D1 (0.53) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3291702 | 0.82 | CACNA2D1 (0.53) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL15969817 | 0.82 | CACNA2D1 (0.53) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3291696 | 0.82 | CACNA2D1 (0.53) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120084903-A | Method for detecting related substances in 3-isobutyl glutaric anhydride | 河北圣雪大成制药有限责任公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120037202-A | Lipid nanoparticle based on cationic lipid with branched structure at junction and application of lipid nanoparticle | 浙江大学 | 2025-05-27 | — | — | CN | claimed |
| CN-118702912-A | Preparation method of spontaneously degradable cyclic poly (ester-peptide), product and degradation method thereof | 浙江大学 | 2024-09-27 | — | — | CN | claimed |
| CN-118271586-A | Method for synthesizing polyester by ionic liquid catalysis | 福州大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118271570-A | Preparation method of organic phosphine-terminated non-conjugated oxygen-enriched fluorescent polymer, and product and application thereof | 浙江大学 | 2024-07-02 | — | — | CN | claimed |
| CN-116143743-A | Preparation process and preparation device of 3-isobutyl glutaric anhydride | 太仓市茜泾化工有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116084181-A | Flexible stab-resistant and bulletproof textile and manufacturing method thereof | 西京学院 | 2023-05-09 | — | — | CN | claimed |
| CN-112280431-A | Heating coating containing carbon nano tube and having positive temperature coefficient effect and preparation method thereof | 华碳创新(广东)材料技术有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-105085302-B | Pregabalin intermediate mother liquor and wastewater reuse method | 浙江华海药业股份有限公司 | 2020-09-15 | — | — | CN | claimed |
| EP-3275860-B1 | METHOD FOR PREPARING PREGABALIN INTERMEDIATE 3-CARBAMOYMETHYL-5-METHYLHEXANOIC ACID WITHOUT SOLVENT | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2020-02-26 | — | — | EP | claimed |
| US-20120277437-A1 | KINETIC RESOLUTION | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY (IE) | 2012-11-01 | — | — | US | claimed |
| WO-2012093411-A2 | PROCESS FOR THE PREPARATION OF R-(-)-3- (CARBAMOYLMETHYL)-5-METHYLHEXANOIC ACID AND THE INTERMEDIATES | DR BRAJA SUNDAR PRADHAN (IN) | 2012-07-12 | — | — | WO | claimed |
| US-20120046468-A1 | INTERMEDIATES IN THE ENANTIOSELECTIVE SYNTHESIS OF 3-(AMINOMETHYL)-5-METHYL-HEXANOIC ACID | THE PROVOST,FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY LAND AND UNDIVIDED TRINITY OF QUEEN ELIZ (IE) | 2012-02-23 | — | — | US | claimed |
| EP-2332895-A1 | Kinetic Resolution | The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin (IE) | 2011-06-15 | — | — | EP | claimed |
| EP-2213659-A1 | Intermediates in the Enantioselective Synthesis of 3-(Aminomethyl)-5-Methyl-Hexanoic Acid | The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin (IE) | 2010-08-04 | — | — | EP | claimed |
| EP-2019817-A2 | PROCESSES FOR THE PREPARATION OF R-(+)-3-(CARBAMOYL METHYL)-5-METHYLHEXANOIC ACID AND SALTS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-02-04 | — | — | EP | claimed |
| WO-2009004643-A2 | AN IMPROVED PROCESS FOR PREPARATION OF (S)-PREGABALIN AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2009-01-08 | — | — | WO | claimed |
| US-7462738-B2 | Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-12-09 | — | — | US | claimed |
| US-20070293694-A1 | Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-12-20 | — | — | US | claimed |
| WO-2007139933-A2 | PROCESSES FOR THE PREPARATION OF R-(+)-3-(CARBAMOYL METHYL)-5-METHYLHEXANOIC ACID AND SALTS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-12-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277437-A1 | KINETIC RESOLUTION | SPR, ADH5, ADH1C | CACNA2D1 4724/4885CACNB3 2975/4885CACNA1C 3442/4885 |
| US-20070293694-A1 | Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof | RIMKLA, GABRE, GRIK5 | CACNA2D1 245/4885CACNB3 63/4885CACNA1C 43/4885 |
| US-20120046468-A1 | INTERMEDIATES IN THE ENANTIOSELECTIVE SYNTHESIS OF 3-(AMINOMETHYL)-5-METHYL-HEXANOIC ACID | FAAH, ALDH7A1, GABRE | CACNA2D1 1001/4885CACNB3 1586/4885CACNA1C 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.