Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964687 | 0.92 | CES1 (0.39) | MAPK1CES1CA2CA4PTPN1 | |
| SCHEMBL545780 | 0.89 | CES1 (0.34) | MAPK1CES1CA2CA4PDK1 | |
| SCHEMBL29745841 | 0.89 | CES1 (0.34) | MAPK1CES1CA2CA4PDK1 | |
| SCHEMBL1573975 | 0.87 | THRB (0.39) | MAPK1CES1CA2CA4HDAC3 | |
| SCHEMBL29746113 | 0.87 | THRB (0.39) | MAPK1CES1CA2CA4HDAC3 | |
| SCHEMBL4962904 | 0.87 | HDAC1 (0.40) | CES1CA2CA4PTPN1HDAC3 | |
| SCHEMBL4962900 | 0.86 | THRB (0.42) | CES1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL4962460 | 0.86 | THRB (0.42) | CES1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL4962222 | 0.86 | THRB (0.42) | CES1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL4962404 | 0.86 | THRB (0.42) | CES1CA2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434091-A1 | CHEMICAL-AMPLIFICATION-TYPE POSITIVE RADIATION-SENSITIVE RESIN COMPOSITION | Clariant International Ltd. (CH) | 2004-06-30 | — | — | EP | disclosed |
| US-20040033438-A1 | Chemical-amplication-type positive radiation-sensitive resin composition | AZ ELECTRONIC MATERIALS USA CORP. | 2004-02-19 | — | — | US | disclosed |