SCHEMBL665663

SCHEMBL665663

C=CC(=O)OCC([SiH3])(OCCOC)OCCOC

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
CYP3A4 P08684 2/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
THRB P10828 2/20 0.41
TSHR P16473 7/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL665501 0.85 TSHR (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL4360498 0.83 TSHR (0.49) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL663277 0.81 ALDH1A1 (0.48) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL663437 0.80 ALDH1A1 (0.52) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL664175 0.77 THRB (0.40) ALDH1A1THRBTSHR
SCHEMBL38483 0.76
Ethylene SCHEMBL23130998 0.74 TSHR (0.64) ALDH1A1TP53HIF1ACYP3A4MAPK1
Ethylene SCHEMBL15417912 0.74 TSHR (0.64) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL15841507 0.74 TSHR (0.64) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL6037085 0.73 ALDH1A1 (0.44) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2941460-B1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2017-11-22 EP disclosed
US-9683125-B2 One-component, curable coating compositions, processes for making and using them, and coatings and articles prepared with them BASF COATINGS GMBH (DE) 2017-06-20 US disclosed
US-20150337159-A1 One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them BASF COATINGS GMBH (DE) 2015-11-26 US disclosed
EP-2941460-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF Coatings GmbH (DE) 2015-11-11 EP disclosed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US disclosed
WO-2014106552-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2014-07-10 WO disclosed
US-20120045586-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF BASF COATINGS GMBH (DE) 2012-02-23 US disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed