SCHEMBL663277

SCHEMBL663277

C=CC(=O)OCC([SiH3])(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP3A4 P08684 2/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
THRB P10828 3/20 0.45
TSHR P16473 8/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.39
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL665501 0.86 TSHR (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL17922841 0.82 TSHR (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL12394810 0.81 ALDH1A1 (0.48) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL663437 0.81 ALDH1A1 (0.52) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL8731570 0.81 ALDH1A1 (0.52) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL665663 0.81 ALDH1A1 (0.44) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL28520107 0.81 ALDH1A1 (0.44) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL9229975 0.80 TSHR (0.56) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL21066641 0.78 TSHR (0.55) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL29026109 0.78 THRB (0.49) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895353-A Preparation method of FEVE coating 江苏考普乐新材料股份有限公司 2023-04-04 CN claimed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US claimed
EP-2414466-B1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS GMBH (DE) 2013-10-16 EP claimed
US-20120045586-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF BASF COATINGS GMBH (DE) 2012-02-23 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
CN-117983518-A Method for manufacturing laminated structure and use thereof 株式会社钟化 2024-05-07 CN disclosed
CN-115975444-A FEVE coating 江苏考普乐新材料股份有限公司 2023-04-18 CN disclosed
CN-115895353-A Preparation method of FEVE coating 江苏考普乐新材料股份有限公司 2023-04-04 CN disclosed
CN-112424269-B Resin composition for foam, and method for producing foam 株式会社钟化 2023-02-28 CN disclosed
EP-3392036-B1 METHOD FOR PRODUCING LAMINATE, AND LAMINATE KANEKA CORP (JP) 2022-03-30 EP disclosed
CN-109803826-B Laminate and method for producing same 信越化学工业株式会社 2021-05-11 CN disclosed
CN-108472685-B Method for producing laminate 信越化学工业株式会社 2021-02-02 CN disclosed
EP-3045506-A1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE Shin-Etsu Chemical Co., Ltd. (JP) 2016-07-20 EP disclosed
US-20150337159-A1 One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them BASF COATINGS GMBH (DE) 2015-11-26 US disclosed
EP-2941460-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF Coatings GmbH (DE) 2015-11-11 EP disclosed
CN-104884552-A ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH 2015-09-02 CN disclosed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US disclosed
WO-2014106552-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2014-07-10 WO disclosed
US-20120045586-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF BASF COATINGS GMBH (DE) 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 ALDH1A1 402/4885TP53 4663/4885HIF1A 3260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.