SCHEMBL664175

SCHEMBL664175

C=C(C)C(=O)OCC([SiH3])(OCCOC)OCCOC

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15864506 0.85 TSHR (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4358822 0.83 TSHR (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL580728 0.81 THRB (0.47) THRBTSHRALDH1A1
SCHEMBL396763 0.80 TSHR (0.44) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL665663 0.77 ALDH1A1 (0.44) THRBTSHRALDH1A1
SCHEMBL27357 0.76 THRB (0.63) THRBTSHRALDH1A1POLBAPEX1
Hydroxyl Radical SCHEMBL28295756 0.74 THRB (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6332146 0.73 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL393525 0.72 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL665496 0.72 TSHR (0.48) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2941460-B1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2017-11-22 EP disclosed
US-9683125-B2 One-component, curable coating compositions, processes for making and using them, and coatings and articles prepared with them BASF COATINGS GMBH (DE) 2017-06-20 US disclosed
US-20150337159-A1 One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them BASF COATINGS GMBH (DE) 2015-11-26 US disclosed
EP-2941460-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF Coatings GmbH (DE) 2015-11-11 EP disclosed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US disclosed
WO-2014106552-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2014-07-10 WO disclosed
US-20120045586-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF BASF COATINGS GMBH (DE) 2012-02-23 US disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed