Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17426973 | 0.94 | ADH1B (0.41) | ADH1BADH1CADH1A | |
| SCHEMBL17426952 | 0.94 | ADH1B (0.41) | ADH1BADH1CADH1A | |
| SCHEMBL6658499 | 0.94 | ADH1B (0.41) | ADH1BADH1CADH1A | |
| SCHEMBL3340519 | 0.77 | THRB (0.41) | ADH1BADH1CADH1A | |
| SCHEMBL8989800 | 0.77 | CA1 (0.39) | ADH1BADH1CADH1A | |
| SCHEMBL4417025 | 0.77 | THRB (0.41) | ADH1BADH1CADH1A | |
| SCHEMBL25887063 | 0.77 | CA1 (0.39) | ADH1BADH1CADH1A | |
| SCHEMBL7798717 | 0.77 | CA1 (0.39) | ADH1BADH1CADH1A | |
| Trifluoromethanesulfonic Acid SCHEMBL6657468 | 0.77 | ADH1B (0.32) | ADH1BADH1CADH1A | |
| SCHEMBL25067372 | 0.77 | ADH1B (0.31) | ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160267-B1 | CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE | JAPAN SCIENCE & TECH CORP (JP) | 2004-08-04 | — | — | EP | disclosed |