Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824909 | 0.77 | HTR1A (0.42) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL6658611 | 0.76 | GRM2 (0.35) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL6658608 | 0.76 | GRM2 (0.35) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11916618 | 0.72 | SLC6A2 (0.43) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL6656426 | 0.71 | SLC6A4 (0.45) | SLC6A4L3MBTL1 | |
| SCHEMBL23588427 | 0.70 | SLC6A2 (0.48) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL15676622 | 0.70 | PPARG (0.42) | GRM2L3MBTL1PPARGPPARAALDH1A1 | |
| SCHEMBL7766001 | 0.69 | SLC6A2 (0.41) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL1261700 | 0.69 | ACLY (0.42) | SLC6A2SLC6A4SLC6A3GRM2ALDH1A1 | |
| SCHEMBL31567693 | 0.69 | ACLY (0.42) | SLC6A2SLC6A4SLC6A3GRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |