Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236701 | 0.72 | PPARA (0.46) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL438641 | 0.70 | CTSK (0.41) | ALDH1A1 | |
| SCHEMBL11540623 | 0.69 | TSHR (0.41) | KMT2AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10697022 | 0.69 | MGLL (0.43) | GSK3AGSK3BMGLLFAAHMAOA | |
| SCHEMBL10942039 | 0.69 | TSHR (0.44) | OPRM1OPRD1OPRK1OPRL1DHFR | |
| SCHEMBL1026581 | 0.68 | SMN1; SMN2 (0.39) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL3411538 | 0.67 | MAOA (0.45) | MAOAMAOBOPRM1OPRD1OPRK1 | |
| SCHEMBL21638945 | 0.67 | TSHR (0.43) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL2237483 | 0.66 | TSHR (0.41) | KMT2AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3985723 | 0.66 | MAOA (0.44) | MAOAMAOBOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479669-A1 | Optically active maleimide derivatives and polymaleimides for use as chiral adsorbent in chromatography | Tosoh Corporation (JP) | 2004-11-24 | — | — | EP | disclosed |