Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659184 | 0.92 | ALDH1A1 (0.39) | ALDH1A1BAZ1AMCL1HTTMAPK1 | |
| SCHEMBL6662302 | 0.82 | MAPT (0.46) | ALDH1A1HTTMAPK1LMNAMAPT | |
| SCHEMBL6658616 | 0.80 | MEN1 (0.51) | ALDH1A1HTTMAPK1TDP1LMNA | |
| SCHEMBL6657379 | 0.80 | MAPT (0.53) | ALDH1A1KDM4EHTTMAPK1LMNA | |
| SCHEMBL6658613 | 0.79 | PPARG (0.46) | ALDH1A1MCL1KDM4EHTTMAPK1 | |
| SCHEMBL6658355 | 0.79 | ALOX5 (0.41) | ALDH1A1KDM4EHTTMAPK1LMNA | |
| SCHEMBL6664855 | 0.77 | MAOB (0.52) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL6658434 | 0.77 | MEN1 (0.42) | ALDH1A1KDM4EHTTMAPK1LMNA | |
| SCHEMBL6656945 | 0.77 | MEN1 (0.48) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL6662202 | 0.76 | MAPT (0.60) | ALDH1A1TDP1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |