SCHEMBL6659575

SCHEMBL6659575

Nc1ccc(S(=O)(=O)c2ccc(N)c(N)c2)cc1N

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.83
PKM P14618 3/20 0.83
HTR6 P50406 2/20 0.83
GAA P10253 3/20 0.64
MAPT P10636 2/20 0.64
KMT2A Q03164 5/20 0.61
MEN1 O00255 3/20 0.61
KDM4E B2RXH2 2/20 0.61
RAB9A P51151 1/20 0.61
LMNA P02545 3/20 0.52
CYP2C9 P11712 2/20 0.52
TSHR P16473 2/20 0.52
MPO P05164 1/20 0.52
CYP3A4 P08684 1/20 0.52
CA12 O43570 5/20 0.46
CA1 P00915 5/20 0.46
CA2 P00918 5/20 0.46
CA9 Q16790 5/20 0.46
CA4 P22748 4/20 0.46
CA6 P23280 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484233 1.00 ALDH1A1 (0.83) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL29462648 1.00 ALDH1A1 (0.83) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL636445 1.00 ALDH1A1 (0.83) ALDH1A1PKMHTR6GAAMAPT
Hydrochloric Acid SCHEMBL7873578 0.97 ALDH1A1 (0.79) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL728291 0.91 HTR6 (1.00) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL30771551 0.91 HTR6 (1.00) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL30166976 0.89 HTR6 (0.74) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL950448 0.89 HTR6 (0.74) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL28822994 0.87 ALDH1A1 (0.71) ALDH1A1PKMHTR6GAAMAPT
SCHEMBL27677623 0.87 ALDH1A1 (0.71) ALDH1A1PKMHTR6GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2882822-B1 HYBRID THERMOPLASTIC GELS AND THEIR METHOD OF MAKING COMMSCOPE TECHNOLOGIES LLC (US) 2019-10-30 EP claimed
EP-0955317-B1 Grafted maleimide-styrene-g-polypropylene copolymers used in rubber compounds for increasing hysteresis BRIDGESTONE CORP (JP) 2004-08-04 EP claimed