Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | HCK | P08631 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6662598 | 0.99 | MAOA (0.40) | MAOAMAOBAPPGHSRNPC1 | |
| SCHEMBL6661847 | 0.88 | MAOA (0.38) | MAOAMAOBGHSRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6660875 | 0.87 | MEN1 (0.38) | GHSRNPC1RAB9AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6666456 | 0.87 | NPC1 (0.37) | MAOAMAOBGHSRNPC1RAB9A | |
| SCHEMBL6660906 | 0.86 | MAOA (0.44) | MAOAMAOBAPPNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6661781 | 0.85 | MAOA (0.43) | MAOAMAOBAPPNPC1RAB9A | |
| SCHEMBL6661798 | 0.83 | SRC (0.34) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL6660988 | 0.82 | ALDH1A1 (0.35) | NPC1RAB9AKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6664936 | 0.81 | ALDH1A1 (0.35) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL6660415 | 0.80 | MAPT (0.43) | NPC1RAB9AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268436-B1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-08-18 | — | — | EP | claimed |
| US-6600050-B2 | Inorganic and organic acids and agents, containing these compounds, for the oxidative dyeing of fibers such as hair for hair dyes | WELLA AG (DE) | 2003-07-29 | — | — | US | claimed |
| US-20030115684-A1 | Novel diaminopyrazole derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | claimed |
| EP-1268436-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | claimed |
| WO-2002072556-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-19 | — | — | WO | claimed |
| EP-1268436-B1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-08-18 | — | — | EP | disclosed |
| US-6600050-B2 | Inorganic and organic acids and agents, containing these compounds, for the oxidative dyeing of fibers such as hair for hair dyes | WELLA AG (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20030115684-A1 | Novel diaminopyrazole derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | disclosed |
| EP-1268436-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2002072556-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030115684-A1 | Novel diaminopyrazole derivatives and dyes containing said compounds | AOC1, DPYD, PPOX | MAOA 149/4885MAOB 113/4885APP 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.