SCHEMBL6659986

SCHEMBL6659986

CC(c1ccc(N)cc1)c1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TP53 P04637 3/20 0.58
CYP3A4 P08684 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
HSD17B10 Q99714 3/20 0.48
TAAR1 Q96RJ0 2/20 0.48
ESR1 P03372 1/20 0.46
PDCD1 Q15116 1/20 0.46
ESR2 Q92731 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
GRIA4 P48058 1/20 0.46
MEN1 O00255 3/20 0.42
MAPT P10636 3/20 0.42
KMT2A Q03164 3/20 0.42
KIF11 P52732 2/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8095943 0.92 ESR1 (0.52) ALDH1A1TP53CYP3A4TDP1HSD17B10
SCHEMBL8164161 0.92 ESR1 (0.52) ALDH1A1TP53CYP3A4TDP1HSD17B10
SCHEMBL140799 0.92 ESR1 (0.52) ALDH1A1TP53CYP3A4TDP1HSD17B10
SCHEMBL3482829 0.92 ESR1 (0.52) ALDH1A1TP53CYP3A4TDP1HSD17B10
SCHEMBL256589 0.86 ALDH1A1 (0.61) ALDH1A1TP53CYP3A4TDP1HSD17B10
SCHEMBL4672030 0.82 TSHR (0.48) ALDH1A1CYP3A4TDP1HSD17B10TAAR1
SCHEMBL20132351 0.82 ACHE (0.65) ALDH1A1TP53CYP3A4TDP1TAAR1
SCHEMBL29225750 0.82 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4TDP1HSD17B10
SCHEMBL22593785 0.82 ACHE (0.65) ALDH1A1TP53CYP3A4TDP1TAAR1
SCHEMBL20132340 0.82 ACHE (0.65) ALDH1A1TP53CYP3A4TDP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004319448-A VACUUM ENVELOPE FOR IMAGE DISPLAY DEVICE, SEALANT FOR IMAGE DISPLAY DEVICE, IMAGE DISPLAY DEVICE, AND SEALING METHOD OF VACUUM ENVELOPE FOR IMAGE DISPLAY DEVICE MITSUI CHEMICALS INC 2004-11-11 JP disclosed