Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25014555 | 0.93 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| SCHEMBL5955 | 0.91 | MAPT (0.53) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| Hydrochloric Acid SCHEMBL4372842 | 0.88 | MEN1 (0.50) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| Ammonia Solution, Strong SCHEMBL28370828 | 0.88 | MAPT (0.50) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| Water SCHEMBL4672027 | 0.88 | MAPT (0.50) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| Hydrochloric Acid SCHEMBL1586648 | 0.88 | MEN1 (0.50) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| SCHEMBL197335 | 0.88 | KIF11 (0.52) | TP53NPC1RAB9AKDM4EKIF11 | |
| Benzidine SCHEMBL28946931 | 0.87 | TAAR1 (0.64) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| SCHEMBL8675147 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TP53CYP3A4TDP1NPC1 | |
| SCHEMBL6659986 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TP53CYP3A4TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177498-A2 | HEXAVALENT SUBSTITUTED BENZENES | NORTHEASTERN UNIVERSITY (US) | 2023-09-21 | — | — | WO | disclosed |
| US-11339184-B2 | Antibacterial compounds, compositions thereof, and methods using same | THE ROCKEFELLER UNIVERSITY (US) | 2022-05-24 | — | — | US | disclosed |
| WO-2021242849-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | THE ROCKEFELLER UNIVERSITY (US) | 2021-12-02 | — | — | WO | disclosed |
| US-20210024562-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | THE ROCKEFELLER UNIVERSITY | 2021-01-28 | — | — | US | disclosed |
| US-10398783-B2 | Antiproliferative compounds and conjugates made therefrom | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-03 | — | — | US | disclosed |
| US-9999905-B2 | Polymeric coatings and coating method | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-20180110873-A1 | ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM | BRISTOL-MYERS SQUIBB COMPANY | 2018-04-26 | — | — | US | disclosed |
| WO-2018075842-A1 | CONDENSED BENZODIAZEPINE DERIVATIVES AND CONJUGATES MADE THEREFROM | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-26 | — | — | WO | disclosed |
| US-20180110873-A1 | ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM | BRISTOL-MYERS SQUIBB COMPANY | 2018-04-26 | — | — | US | disclosed |
| US-20170198165-A1 | POLYMERIC COATINGS AND COATING METHOD | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-07-13 | — | — | US | disclosed |
| WO-2012028825-A1 | ULTRA-THIN FILMS OF MOLECULARLY IMPRINTED POLYMERS CONFINED TO THE SURFACE OF A SUBSTRATE | UNIVERSITE PARIS DIDEROT-PARIS 7 (FR) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012002569-A1 | METHOD FOR FORMING MULTILAYER COATING FILM | KANSAI PAINT CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
| EP-1694281-A4 | BIPHENYL COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2008-12-24 | — | — | EP | disclosed |
| US-20070265345-A1 | Novel Biphenyl Compounds And Their Use | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070259951-A1 | Compounds, Compositions and Methods | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-08 | — | — | US | disclosed |
| EP-1778214-A2 | NOVEL BIPHENYL COMPOUNDS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1694281-A2 | BIPHENYL COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2006020358-A2 | NOVEL BIPHENYL COMPOUNDS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |
| WO-2005060692-A2 | BIPHENYL COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |
| US-6107438-A | AMIDATION A POLYESTER WITH A DIAMINE IN REACTION MIXTURE CONTAINING AN APROTIC PROTOPHOBIC POLAR SOLVENT TO FORM HEAT RESISTANT POLYAMIDEESTER COPOLYMER | M & S RESEARCH AND DEVELOPMENT CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265345-A1 | Novel Biphenyl Compounds And Their Use | KIF5B, KIF5C, KIF5A | ALDH1A1 1524/4885TP53 1153/4885CYP3A4 2663/4885 |
| US-11339184-B2 | Antibacterial compounds, compositions thereof, and methods using same | CLPP, MPO, SPOUT1 | ALDH1A1 3433/4885TP53 1997/4885CYP3A4 4357/4885 |
| US-20070259951-A1 | Compounds, Compositions and Methods | ALPP, PCNA, MKI67 | ALDH1A1 2715/4885TP53 40/4885CYP3A4 4658/4885 |
| US-20180110873-A1 | ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM | MKI67, HDGF, PCLAF | ALDH1A1 314/4885TP53 78/4885CYP3A4 3447/4885 |
| US-20210024562-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | CLPP, MPO, SPOUT1 | ALDH1A1 3433/4885TP53 1997/4885CYP3A4 4357/4885 |
| US-10398783-B2 | Antiproliferative compounds and conjugates made therefrom | MKI67, HDGF, PCLAF | ALDH1A1 314/4885TP53 78/4885CYP3A4 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.